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Serena Jameka Williams (born September 26, 1981) is an American professional tennis player who is a former World No. 1 and currently ranked World No. 4 in singles and No. 5 in doubles with sister Venus Williams. The Women's Tennis Association has ranked her World No. 1 in singles on five separate occasions. She is considered to be one of the greatest women's tennis players of all-time in a career hampered by numerous injuries. She regained this ranking for the fifth time on November 2, 2009. She became the World No. 1 for the first time on July 8, 2002.

Williams is the reigning champion in both singles and women's doubles at the Australian Open, in singles at Wimbledon, and in women's doubles at the French Open. Her 27 Grand Slam titles places her ninth on the all-time list: 13 in singles, 12 in women's doubles, and 2 in mixed doubles. She is the most recent player, male or female, to have held all four Grand Slam singles titles simultaneously and only the fifth woman in history to do so. Her 13 Grand Slam singles titles is sixth on the all-time list. Williams ranks fourth in Grand Slam women's singles titles won during the open era, behind Steffi Graf (22 titles) and Chris Evert and Martina Navratilova (18 titles each). She has won more Grand Slam titles in singles, women's doubles, and mixed doubles than any other active female player.

Williams has won two Olympic gold medals in women's doubles. She has won more career prize money than any other female athlete in history. Serena has played older sister Venus in 23 professional matches since 1998, with Serena winning 13 of these matches. They have met in eight Grand Slam finals, with Serena winning six times. Beginning with the 2002 French Open, they played each other in four consecutive Grand Slam singles finals, which was the first time in the open era that the same two players had contested four consecutive Grand Slam finals. The pair have won 12 Grand Slam doubles titles together.

Williams was born in Saginaw, Michigan to Richard Williams and Oracene Price. She is of African American heritage and is the youngest of Oracene's five daughters: half-sisters Yetunde (died September 14, 2003), Lyndrea and Isha Price, and older sister Venus. When the children were young, the family moved to the Los Angeles suburb of Compton, where Serena started playing tennis at the age of five. Her father home-schooled Williams and her sister Venus. To this end, Williams was and remains coached by both her parents.

Williams's family moved from Compton to West Palm Beach when she was nine so that she could attend the tennis academy of Rick Macci, who would provide additional coaching. Macci spotted the exceptional talents of the sisters. He did not always agree with Williams's father but respected that "he treated his daughters like kids, allowed them to be little girls". Richard stopped sending his daughters to national junior tennis tournaments when Williams was 10, since he wanted them to take it slow and focus on school work. Another motivation was racial, as he had allegedly heard parents of white players talk about the Williams sisters in a derogatory manner during tournaments. At that time, Williams had a 46–3 record on the United States Tennis Association junior tour and was ranked No. 1 among under 10 players in Florida. In 1995, Richard pulled his daughters out of Macci's academy, and from then on took over all coaching at their home. When asked in 2000 whether having followed the normal path of playing regularly on the junior circuit would have been beneficial, Williams responded: "Everyone does different things. I think for Venus and I, we just tried a different road, and it worked for us."

Williams is primarily a baseline player. Her game is built around taking immediate control of rallies with a powerful and consistent serve (considered by some to be the best in the women's game), return of serve, and forceful groundstrokes from both her forehand and backhand swings. Her serve is technically very sound and has been hit as hard as 129 mph (206.5 km/h), the second-fastest (after her sister Venus) all-time among female players.

Williams was once known for her unusual and colorful outfits on court. In 2002, there was much talk when she wore a black lycra catsuit at the US Open. At the 2004 US Open, Williams wore denim skirts and knee-high boots—tournament officials, however, did not allow her to wear the boots during matches. At Wimbledon in 2008, the white trench coat she wore during warm-up for her opening match was the subject of much discussion since it was worn despite the sunny weather. Off-court, Williams has also presented new designs. In November 2004, at the London premiere of After the Sunset she wore a red gown that had a near-topless effect.

Williams formerly had a special line with Puma and currently has a line with Nike. The deal with Nike is worth US$40 million and was signed in April 2004. Since 2004, she has also been running her own line of designer apparel called "Aneres"—her first name spelled backward. In 2009 she launched a signature collection of handbags and jewelry. The collection, called Signature Statement, is sold mainly on the Home Shopping Network (HSN).

Williams has appeared on television and also provided voice work on animated shows: in a 2001 episode of The Simpsons Serena joined the animation along with sister Venus, Pete Sampras and Andre Agassi. She has also provided guest voice work in a 2005 episode of Playhouse Disney's animated kids show Higglytown Heroes and a 2007 episode of the Nickelodeon cartoon Avatar: The Last Airbender, which she has described as her "favorite show".

Williams has posed for the 2003 and 2004 editions of the Sports Illustrated Swimsuit Issue. In April 2005, MTV announced plans to broadcast a reality show around the lives of Serena and Venus, which was eventually aired on ABC Family. Williams has appeared twice on MTV's Punk'd and in 2007, appeared in the ABC reality television series Fast Cars and Superstars: The Gillette Young Guns Celebrity Race. In 2002, she played Miss Wiggins in the season 3 episode "Crouching Mother, Hidden Father" of My Wife and Kids; she has also guest-starred during episodes of ER and Law & Order: Special Victims Unit. In 2007 Williams appeared in the music video of "I Want You" by the American rapper Common, alongside performers Alicia Keys and Kanye West.

Serena and sister Venus were mentioned in a couple of songs namely in Super Furry Animals studio album Phantom Power in a track entitle "Venus and Serena", in a single by Snoop Dogg Signs and Ludacris' single My Chick Bad. Miami Dolphins venture.

In August 2009, Serena and Venus Williams became part-owners of the Miami Dolphins. The formal announcement was made during a press conference overlooking the practice field. The Williams are the first African-American females to obtain ownership in an NFL franchise. Other prominent owners include: Jimmy Buffett, Gloria and Emilio Estefan (the first Cuban-American owners), and Marc Anthony and Jennifer Lopez . Stephan Ross, the majority owner of the Dolphins, said "We are thrilled to have Venus and Serena join the Dolphins as limited partners. They are among the most admired athletes in the world and have become global ambassadors for the game of tennis. Their addition to our ownership group further reflects our commitment to connect with aggressively and embrace the great diversity that makes South Florida a multicultural gem."

In 2008 Williams helped to fund the construction of the Serena Williams Secondary School in Matooni, Kenya. She received a Celebrity Role Model Award from Avon Foundation in 2003 for work in breast cancer. Williams has also been involved in a number of clinics at schools and community centers, particularly those which have programs focusing on at-risk youth. She has also won the "Young Heroes Award" from Big Brothers Big Sisters of Greater L.A. and Inland (2003) and the "Family Circle and Prudential Financial Player Who Makes a Difference Award" (2004). In response to the 2010 Haiti earthquake, Williams, along with other ATP and WTA stars decided to forgo their final day of preparation for the 2010 Australian Open to form a charity event in which all proceeds will go to the Haiti earthquake victims.

During the 2009 Wimbledon Championships, Williams said that she is in the process of writing a TV show storyline, which will be converted into script form by her agency. She stated that the show will represent subject matter from a mix of popular American television shows such as Desperate Housewives, Sex and the City, and Family Guy. Serena released her first published work, an autobiography entitled On the Line, following the 2009 US Open.